Chile vs Uruguay Prediction: La Celeste can end with a victory

Chile will be glad to see the back of another disappointing qualifying campaign as their record of two wins, four draws and 11 losses heading into the final game means they have now failed to make three consecutive World Cups. They did earn 19 and 26 points in the previous two qualifying campaigns, though, so their current tally of 10 suggests they are at their lowest point for a long time.

Uruguay have already sealed their spot at next summer’s finals but Marcelo Bielsa is a hard taskmaster and the former Chile boss will expect his talent-filled side to finish with a flourish. Below you can find my Chile vs Uruguay (00:30) predictions.

Team news

Benjamin Kuscevic and Dario Osorio are the big injury absentees for Chile, who will also be without former Watford defender Francisco Sierralta due to suspension.

Uruguay can welcome back Nahitan Nandez and Barcelona’s Ronald Araujo after suspension, but will be without Mathias Oliviera, who picked up his fourth yellow card of qualifying in Friday’s win over Peru.

Chile vs Uruguay odds

Unsurprisingly, Conmebol qualifying’s basement boys Chile are the 12/5 underdogs, with Uruguay an appealing 5/4 and the draw available at 11/5.

Goals have been hard to come by for Chile, so both teams to score is a decent Evens price, with over 2.5 available at big 11/8 odds.

Former Liverpool striker Darwin Nunez is the 9/2 favourite to open the scoring.

Uruguay to win @ 5/4

While motivation is low for Uruguay, the ever-demanding Bielsa will not let his players’ energy levels drop, with the experienced Argentine knowing momentum is so important ahead of international tournaments.

La Celeste have bounced back from a shock 2-0 defeat at Paraguay to beat bottom-four sides Venezuela and Peru to nil, suggesting a trip to managerless basement boys Chile should be no issue at all.

It was a comfortable 3-1 win for Uruguay in the reverse fixture and with their hosts losing three straight games without scoring, it should be similarly plain-sailing in the early hours of Wednesday morning.

Giorgian de Arrascaeta anytime goalscorer @ 11/4

Midfielder Giorgian de Arrascaeta may not be the most well-known Uruguayan among European fans, with the enigmatic Nunez or Real Madrid’s Fede Valverde surely taking that title, but he may very well be the most in-form right now.

The Flamengo star has scored 12 goals and provided 10 assists in 19 Brazilian Serie A games in 2025 and he is only getting better, having netted four and creating four more strikes in his last six matches for club and country.

De Arrascaeta has found the net in two straight games for La Celeste and can extend that streak against Chile, who have managed just two clean sheets in 12 matches.

Giorgian de Arrascaeta anytime goalscorer @ 11/4

Midfielder Giorgian de Arrascaeta may not be the most well-known Uruguayan among European fans, with the enigmatic Nunez or Real Madrid’s Fede Valverde surely taking that title, but he may very well be the most in-form right now.

The Flamengo star has scored 12 goals and provided 10 assists in 19 Brazilian Serie A games in 2025 and he is only getting better, having netted four and creating four more strikes in his last six matches for club and country.

De Arrascaeta has found the net in two straight games for La Celeste and can extend that streak against Chile, who have managed just two clean sheets in 12 matches.

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