Spurs and Newcastle will be both be aiming to rectify their midweek defeats when the sides meet at the Tottenham Hotspur Stadium on Sunday afternoon (16:30).
The hosts were beaten by London rivals West Ham United, while Newcastle were stunned at Goodison Park by relegation-threatened Everton.
Ivan Perisic, James Maddison, Rodrigo Bentancur, Micky van de Ven, Eric Dier, Manor Solomon, Ryan Sessegnon and Alfie Whiteman are all on the treatment table for the hosts.
As for Newcastle, Sandro Tonali remains suspended while Nick Pope, Dan Burn, Sven Botman, Jamaal Lascelles, Matt Targett and Javier Manquillo will be absent due to injury.
They’re joined in the treatment room by Jacob Murphy, Sean Longstaff, Elliot Anderson, Joe Willock, Harvey Barnes and Callum Wilson.
Spurs are 23/20 to get back to winning ways here, while Newcastle are 2/1 to upset the hosts, and the draw is 11/4.
Draw and both teams to score @ 16/5
Both sides have multiple injuries within their ranks, which is one reason why I'm struggling to split the teams.
The feel-good factor surrounding Spurs earlier in the campaign seems to have disappeared, as they've failed to win any of their last five outings. Tottenham had an incredible 23 shots against West Ham on Thursday but just couldn't convert with only seven on target.
I've said it in multiple columns previously, but I'll repeat myself again here; Newcastle are a completely different outfit at home compared to on the road, and the results show that. Near-perfect at home this season, the Toon Army have only managed a single win on their travels in the league.
These two normally serve up a cracker, with the Magpies hammering Spurs 6-1 at St James' Park last season after an early onslaught of goals.
In fact, there's been 25 goals in the last five runnings of this fixture in the league, with both teams scoring in the last seven times they've met.
Anthony Gordon to score anytime @ 12/5
The former Everton man endured a miserable return to his old stomping ground in midweek but the 22-year-old has emerged as one of Newcastle's most important players this season.
He scored the winner against Manchester United last weekend in what was a fine performance, becoming the first Newcastle player to score in four consecutive home Premier League appearances since Joe Willock in May 2021.
Now he just to to the business away from home for the Toon Army, and he'll get chances against this Spurs side, who are without a clean sheet in six.
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