Borussia Dortmund vs Bayer Leverkusen Prediction: Kofane to double up on Dortmund

 | Tuesday 2nd December 2025, 7:45am

Tuesday 2nd December 2025, 7:45am

Signal iduna park westfalenstadion borussia dortmund scaled

Borussia Dortmund and Bayer Leverkusen were only in action against each other a matter of days ago, with the former winning 2-1 in the Bundesliga at the latter’s BayArena on Saturday. Leverkusen can quickly exact revenge, though, as they face off again on Tuesday (20:00 GMT, Premier Sports Player), this time in the DFB-Pokal, at BVB's Signal Iduna Park.

Below are my Borussia Dortmund vs Bayer Leverkusen predictions, supported by all the latest team news and match odds.

Borussia Dortmund vs Bayer Leverkusen Betting Tips

  • Anytime Goalscorer - Christian Kofane (B04) @ 21/10
  • Booking Points Over/Under +42.5 - Over 42.5 @ 6/5

*Odds correct as of the time of publication

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Team News

Niklas Sule (toe) and Max Beier (muscle) missed the weekend trip to Leverkusen due to injury, and both look set to miss out again on Tuesday.

Football Odds

The visitors, meanwhile, have several players sidelined, including Ezequiel Fernandez (knee), Arthur (back), Exequiel Palacios (groin), Axel Tape (hamstring) and Lucas Vazquez (muscle).

Borussia Dortmund vs Bayer Leverkusen Predicted Lineups

  • Borussia Dortmund: Kobel; Anselmino, Anton, Schlotterbeck; Ryerson, Sabitzer, Nmecha, Svensson; Brandt, Adeyemi; Guirassy
  • Bayer Leverkusen: Flekken; Andrich, Bade, Tapsoba; Hofmann, Maza, Garcia, Grimaldo; Tillman, Poku; Kofane

Borussia Dortmund vs Bayer Leverkusen Odds

Dortmund have won the last two head-to-heads, although they are winless in their last two home games against Leverkusen, last beating Die Werkself at Signal Iduna Park in August 2022 (1-0).

Tuesday’s hosts are 4/5 to triumph inside regulation time this week, implying a 55.6% probability of success, while the visitors are 11/4, or a 26.7% chance, to claim a second stadium victory of the calendar year, following January’s 3-2 win there under now-Real Madrid head coach Xabi Alonso.

The draw, which would send the tie to extra time, is also priced at 11/4, while Dortmund are 4/9 and 13/8, respectively, to win the tie by any means.

Borussia Dortmund vs Bayer Leverkusen Stats

  • Kofane (B04) has scored five times this season (including v DOR last Saturday)
  • Five of the last seven H2Hs have produced over 42.5 booking points
  • Saturday's H2H saw seven yellows (70 booking points) issued

Anytime Goalscorer - Christian Kofane (B04) @ 21/10

Leverkusen's Christian Kofane has made a great start to life in Germany, following his summer switch from La Liga 2 club Albacete, where he scored eight goals in 20 appearances last season.

The 19-year-old has notched in all three competitions he has featured in for Leverkusen, netting three times in 11 Bundesliga appearances (four starts), once in five Uefa Champions League games (four starts), and once in two DFB-Pokal substitute outings.

Today's Football Fixtures

After coming off the bench in the 63rd minute on the weekend and finding the back of the net 20 minutes later, Kofane has surely done enough to start at Signal Iduna Park on Tuesday, and that makes him great value in the Anytime Goalscorer market at 21/10.

The Cameroonian has already shown he can breach Dortmund's defence with limited minutes, so with more game time in midweek, he will fancy his chance of scoring at least once.

Borussia Dortmund vs Bayer 04 Leverkusen - Anytime Goalscorer
Christian Kofane

Odds correct at time of publishing.

Booking Points Over/Under +42.5 - Over 42.5 @ 6/5

Five of the last seven head-to-heads, including Saturday's, have seen the above selection land.

Seven yellow cards, amounting to 70 booking points, were totalled in Dortmund's weekend win at the BayArena, where the hosts were issued three cautions to their opponents' four.

Leverkusen's two previous matches in the competition this season, a 4-0 win at Grossaspach (August 15) and a 4-2 extra-time victory at Paderborn (October 29), have produced 100 and 45 (75 including extra time) booking points, respectively.

We may not see as many cards as on the weekend, but given the importance of the tie and the quick turnaround, I'm expecting more feistiness on Tuesday, and so backing over 42.5 booking points looks like a sensible selection.

Borussia Dortmund vs Bayer 04 Leverkusen - Booking Points Over/Under +42.5
Over 42.5

Odds correct at time of publishing.

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