Atletico Madrid vs Inter Milan Prediction: Atleti to end Inter’s UCL winning streak

 | Wednesday 26th November 2025, 6:00am

Wednesday 26th November 2025, 6:00am

Inter Milan will hope to continue their perfect run of form in the Champions League as they visit the Metropolitano Stadium on Wednesday night to take on Atletico Madrid (20:00 GMT, TNT Sports 6).

Below you can find my Atletico Madrid vs Inter Milan predictions featuring team news and betting tips. 

Atletico Madrid vs Inter Milan Betting Tips

  • Atletico Madrid to win @ 5/4
  • Julian Alvarez to score first @ 4/1

*Odds correct as of the time of publication

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Team News

Jan Oblak could miss this game for the hosts, meaning that Juan Musso could be in line for his first European appearance of the season, having kept Getafe at bay last time out. Oblak could join Marcos Llorente and Robin Le Normand on the sidelines with the latter out with a knee issue.

Antoine Griezmann was rested over the weekend and will hope to partner Julian Alvarez up top, although Alexander Sorloth and Giacomo Raspadori are both pushing to be in the XI. 

Alvarez’s international teammate Lautaro Martinez will start up top for Inter Milan, and is set to make his 50th start in this competition. Marcus Thuram could partner him, while unfortunately for Cristian Chivu, Denzel Dumfries, Henrikh Mkhitaryan and Matteo Darmian are all absent.

Football Odds

Atletico Madrid vs Inter Milan Predicted Lineups

  • Atletico Madrid - Musso; Molina, Gimenez, Hancko, Ruggeri; Simeone, Barrios, Koke, Gonzalez; Griezmann, Alvarez
  • Inter Milan - Sommer; Akanji, Bisseck, Bastoni; Augusto, Barella, Calhanoglu, Zielinski, Dimarco; Martinez, Thuram

Atletico Madrid vs Inter Milan Odds

Atletico Madrid are 5/4 to win this home game against the Italians, giving them an implied win probability of 44%. An away win is priced at 2/1 while a draw is 23/10 for this Champions League encounter. 

Over 2.5 goals is 4/5, BTTS is 8/13 and Alvarez is the favourite to score first at 4/1. 

Atletico Madrid vs Inter Milan Stats

  • Atleti have won their last eight home game
  • Inter Milan have won four from four in the UCL
  • Alvarez has nine goals in 16 appearances this term

Atletico Madrid to win @ 5/4

Inter Milan have been faultless in this season’s Champions League, winning four out of four and conceding just one goal in the process. However, they were shaken by their city rivals last time out as AC Milan secured a vital 1-0 win that dropped Inter to fourth.

Meanwhile, Atleti have been incredible in front of their own fans, winning their last eight home matches on the bounce. Since losing to Arsenal in this competition, they have won five games in a row, and that loss to the Gunners is their only one in their last 11 in all competitions. Diego Simeone has a very strong team at his disposal here, and I’m more than happy to back the home side to end Inter’s winning run in Europe. 

Today's Football Fixtures

Atletico Madrid vs Inter Milan - Match Result
Atletico Madrid

Odds correct at time of publishing.

Julian Alvarez to score first @ 4/1

Alvarez has found some brilliant form this season and seems to have established himself as Atleti’s main man, even above Griezmann. The former Man City man has scored nine goals in 16 appearances this term, and twice in three Champions League outings - so I think he is the most likely candidate to find the net first, at a decent price. 

Atletico Madrid vs Inter Milan - First Goalscorer
Julian Alvarez

Odds correct at time of publishing.

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