Chiefs vs Bills Predictions: Can the Chiefs maintain their perfect record?

The Kansas City Chiefs look to maintain their perfect record when they travel to Highmark Stadium to face the Buffalo Bills on Sunday evening (21:25, live on Sky Sports NFL).
The Chiefs are 9-0 heading into this contest, while the Bills are on a five-game winning streak themselves, making this game the biggest of the NFL season so far. Read on for my Chiefs vs Bills prediction, as well as the latest match odds and team news.
Team News
Sean McDermott has ruled out rookie Keon Coleman for Buffalo as the wide receiver picked up an injury in the closing minutes against Miami at the start of the month.
Curtis Samuel has played the last two weeks for the Bills despite being limited throughout practices, while Amari Cooper believes he'll be fit enough for Sunday's encounter.
Spencer Brown injured his ankle in Buffalo’s win at Indianapolis last time out, but he's yet to feature in practice this week, so he's a doubt for this weekend.
As for the visitors, Charles Omenihu and Isiah Pacheco both made their first appearances at practice on Thursday, after long stints on Kansas City’s injured reserve list, although the former is not expected to feature against Buffalo.
JuJu Smith-Schuster could return from a hamstring injury for the Chiefs after participating in Thursday's practice, and Mike Danna is expected to play in Week 11, after making his return from a pectoral injury against the Broncos.
However, one notable absence for Andy Reid is kicker Harrison Butker, who will undergo left knee surgery and miss the next four games.
*Please click on the link above to be taken to the main Chiefs vs Bills page on betfred.com (or app) for all the live betting prices on this match
The Bills are favourites on the moneyline at 10/13, giving them an implied win probability of 56.5%, while Kansas City are 11/10 to keep their perfect record in tact.
The spread is currently set at 1.5 with Buffalo 20/23 to cover, and it's 20/21 for the Chiefs to do the same.
Kansas City Chiefs +1.5 @ 20/21
The Josh Allen v Patrick Mahomes match-up rarely disappoints, and I think we're in for a cracker on Sunday. With a chance to shape the top end of the seedings in the AFC, it really does feel like a play-off game in November.
As mentioned, the Chiefs are undefeated with an 9-0 record, but they've rode their luck in the past few weeks, with back-to-back close calls against the Buccaneers and Broncos.
Buffalo are once again getting an excellent campaign from Josh Allen, but his receiving weapons may be limited on Sunday due to multiple injuries - music to the ears of the Chiefs defence.
Interestingly, this is just the fourth time in the Super Bowl era that a team with a record of 9-0 or better is an underdog - but I find it hard to bet against Patrick Mahomes.
Over the course of his career, Mahomes is a ridiculous 12-1-1 against the spread as an underdog, including an 11-3 straight-up record in those games. However, this is a fading Chiefs offense that keeps relying on late-game heroics. Is it really sustainable?
I think Sunday is geared up to be an closely-fought contest but it wouldn't surprise me if some Mahomes magic wins it late on.
Odds correct at time of publishing.
Under 46.5 points @ 20/23
The Chiefs have rode their luck in recent weeks, as mentioned above, and this isn't the free-flowing, high-scoring offence that we've seen over the past couple of seasons.
Normally, both quarterbacks tend to let it rip in these match-ups but Kansas City have struggled to get things going attacking-wise, while the Buffalo offence will be depleted by injuries this weekend.
I can see the Chiefs opting to grind this one out and run the ball more, limiting the possessions for the hosts, so I'm taking the under on the points total.
Odds correct at time of publishing.
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